Acute poststreptococcal glomerulonephritis ( APSGN) - Causes, Symptoms and Treatment
Acute poststreptococcal glomerulonephritis (APSGN) is an inflammation of the kidney tubules (glomeruli) that filter waste products from the blood, following a streptococcal infection such as strep throat. APSGN is also called postinfectious glomerulonephritis.
Glomerulonephritis (GN) is the term generally reserved for the variety of renal diseases in which inflammation of the glomerulus, manifested by proliferation of cellular elements, is secondary to an immunologic mechanism. The modification of this term by the adjective acute (eg, acute glomerulonephritis [AGN], poststreptococcal acute glomerulonephritis [PSAGN]) has imposed temporal restrictions and, as most commonly used by the clinician, defines an almost characteristic clinicopathologic correlation. The term also implies certain distinctive features concerning etiology, pathogenesis, course, and prognosis.
Acute glomerulonephritis often occurs after a streptococcal infection, such as strep throat. When this is the cause, the condition is called acute poststreptococcal glomerulonephritis (APSGN), or postinfectious glomerulonephritis. It can also occur when certain toxins, such as paints or glues, are inhaled and then excreted through the urine. While chronic glomerulonephritis occurs as a symptom of certain diseases, its cause is not known.
Many people do not manifest any symptoms in the early stages of this disease. When symptoms do occur, they may include a low amount of urine or dark, bloody urine, fluid retention and tissue swelling (edema), such as a puffiness of the face and eyelids or swelling in the legs. Brain swelling and high blood pressure may produce headaches, visual disturbances and other serious brain disturbances.
Frequent sore throats and a history of streptococcal infection increase the risk of acquiring APSGN. Some of the main symptoms of APSGN include:
The main goal of any treatment is getting relief from the symptoms and prevent further complications. Vigorous supportive care includes bed rest, fluid and dietary sodium restrictions, and correction of electrolyte imbalances (possibly with dialysis, although this is seldom necessary).
Other Treatment Options for treating glomerulonephritis (ASPGN) may include:
HEALTH CARE | ABOUT US | CONTACT US | BLOG
© 2005 Online-Health-Care.com. All rights reserved.
Disclaimer: Online-Health-Care.com is for informational purposes only and is not intended to act as a substitute for a professional healthcare practitioner advise. For specific medical advice, diagnoses, and treatment, please consult your doctor. We will not be liable for any complications, injuries or other medical accidents arising from or in connection with the use of or reliance upon any information on this web site.